New CAD-based lymph node analysis application will be launched by Definiens

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Definiens is all set to launch their first CAD application, LymphExpert, at the European Congress of Radiology in Vienna which will be held from 6-10 March.

The company, which was founded by Gerd Binnig, the 1986 Nobel Laureate in Physics, says LymphExpert is capable of accurately analysing, screening, and sorting high volumes of images, allowing radiologists to operate more efficiently and make more-informed diagnoses. It also helps radiologists to identify, analyse and measure the size of lymph nodes over time, making it easier to detect the metastatic spread of cancer.


A press release issued by Definiens says is the first and only such application capable of automatically segmenting images of lymph nodes. It says manual segmentation and analysis of lymph nodes, even by experienced radiologists, is extremely challenging and the results are often inconsistent.


The widely used RECIST and WHO criteria are two-dimensional respectively: manually measured they do not necessarily give a true picture of the size of a lymph node. Volume is a far better measure but, until now, it has not been possible for radiologists to assess the volume of individual lymph nodes.


Consistent, reproducible analysis


Definiens LymphExpert facilitates the manual detection of lymph nodes in a CT image. Once a radiologist identifies a lymph node, the application automatically segments the node and analyses its properties. It quantifies the lymph node according to RECIST and WHO guidelines and visualises its volume. Definiens LymphExpert results are accurate, fast and reproducible, supporting physicians in deciding the most effective course of therapy.


Definiens LymphExpert analyses lymph nodes in 3D and visualises their volume. With a precise, three-dimensional picture of a lymph node’s growth or diminution over time, the cancer’s progression or remission can be more accurately measured.